High-Protein Pizza Pasta Bake (Printable)

Hearty pasta bake with pizza flavors, lean beef, and creamy yogurt-cheese sauce for 37g protein per serving.

# What You'll Need:

→ Proteins

01 - 10.5 oz lean ground beef
02 - 2 oz turkey or regular pepperoni, sliced

→ Pasta

03 - 12 oz high-protein pasta, penne or fusilli

→ Cheese & Yogurt Sauce

04 - 1 cup plain Greek yogurt, 0–2% fat
05 - 1.5 cups part-skim mozzarella cheese, shredded
06 - 0.25 cup grated Parmesan cheese
07 - 1 large egg

→ Vegetables

08 - 1 small onion, finely chopped
09 - 2 cloves garlic, minced
10 - 14 oz canned crushed tomatoes
11 - 1 red bell pepper, diced, optional
12 - 3.5 oz baby spinach, roughly chopped, optional

→ Spices & Seasonings

13 - 1 teaspoon dried oregano
14 - 1 teaspoon dried basil
15 - 0.5 teaspoon chili flakes, optional
16 - Salt and black pepper to taste
17 - Olive oil for sautéing

# Method:

01 - Preheat oven to 400°F. Grease a large baking dish and set aside.
02 - Cook pasta in a large pot of salted boiling water until just al dente. Drain and set aside.
03 - Heat olive oil in a large skillet over medium heat. Add onion and bell pepper if using; sauté 3–4 minutes until softened.
04 - Add minced garlic and cook for 1 minute more.
05 - Add lean ground beef and cook, breaking up with a spoon, until browned and cooked through. Drain excess fat if needed.
06 - Stir in crushed tomatoes, oregano, basil, chili flakes if using, and spinach if using. Simmer for 5 minutes. Season with salt and pepper to taste.
07 - In a bowl, mix Greek yogurt, half of the mozzarella, Parmesan, and egg until smooth. Season lightly with salt and pepper.
08 - Combine cooked pasta, beef-tomato mixture, and yogurt-cheese sauce in a large bowl. Mix well.
09 - Transfer mixture to prepared baking dish. Top with remaining mozzarella and arrange pepperoni slices over the top.
10 - Bake for 20–25 minutes or until bubbly and golden. Let rest for 5 minutes before serving.

# Expert Pointers:

01 -
  • Protein powerhouse – with lean beef, Greek yogurt, and cheese, each serving delivers 37g of muscle-building protein
  • Two comfort foods in one – combines the best of pizza and pasta bakes
  • Make-ahead friendly – prepare in advance and bake when ready
  • Customizable – add your favorite pizza toppings to make it your own
  • Family-approved – even picky eaters love this cheesy, flavorful casserole
02 -
  • For meal prep: Assemble the entire casserole, cover tightly, and refrigerate for up to 24 hours before baking. Add an extra 5-10 minutes to the baking time if coming straight from the refrigerator.
  • Create a protein boost by adding a scoop of unflavored protein powder to the yogurt-cheese mixture – it blends in seamlessly.
  • For extra flavor depth, deglaze the pan with a splash of red wine after browning the beef (before adding tomatoes).
  • To reduce calories while maintaining protein, use fat-free Greek yogurt and part-skim mozzarella.
  • For a crispy topping, sprinkle with additional Parmesan in the last 5 minutes of baking and briefly broil until golden.
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